Fundamentals of Genetics (Paper Code: 17010204) | ||
Theory
Definition and terminology used in genetics; ultra structure of cells, Mendelian inheritance, exceptions to the Mendel’s laws; gene interaction; multiple alleles pleiotropism, penetrance and expressivity
Multiple factor Inheritance & Multiple alleles, cytoplasmic inheritance and its differences from chromosomal inheritance.
Mutation: Types and methods to induce them, Linkage and its types, Crossing over- type, mechanism and significance cytological proof, Nucleus acids- structure functions type of DNA and RNA. Mutation and its characteristic features; methods of inducing mutations and C l B technique; linkage, types of linkage and estimation of linkage; crossing over and factors affecting it; mechanism of crossing over and cytological proof of crossing over; DNA and it’s structure, function, types, modes of replication and repair; RNA and its structure, function and types. Transcription, Translation, Genetic code, Chromosomal aberration- structural and numerical; gene expression and differential gene activation; lac operon and fine structure of gene Numerical chromosomal aberrations (polyploidy) and evolution of different crop species like cotton, wheat, tobacco, triticale and brassica; structural chromosomal aberrations. |
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Must know |
Desirable to Know | ||
Law of population equilibrium quantitative & qualitative traits. | 1 | Nice to Know |
Practical
Preparation of micro slides and identification of various stages of mitosis; preparation of micro slides and identification of various stages of meiosis; monohybrid ratio and its modifications; dihybrid ratio and its modifications; trihybrid ratio; chi-square analysis and interaction of factors; epistatic factors, supplementary factors and duplicate factors; complementary factors, additive factors and inhibitory factors; linkage – two point test cross; linkage – three point test cross; Hardy Wein Berg law of population equilibrium |
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Syllabus Books
- Phundan Singh 1995Elements of genetics Kalyani Publishers, Ludhiana
- Strickberger, M.W. 1996. Genetics (3rd edn.). Mac Millan Publishing Co., New Delhi
- Winchester A M 1967 Genetics (3 rd edn )Oxford and IBH Publishing Co New Delhi
- Prasad, G. 1989 Introduction to Cytogenetics Kalyani Publishers, Ludhiana
- Gupta P K 2007 Cytogenetics Rastogi Publishers, Meerut
- Swanson, C.P., Merz, T. and Young, J.1975 Cytogenetics Prentice Hall of India Private Limited, New Delhi